PS

*ṣ̂irš- - molar tooth (SED I No. 275, Appleyard 1977:17)

Cf. *ṭirs­ - molar tooth. There is no direct parallel to this root in Mesopotamian Akkadian, but ṣiršu ‘protuberance’ and ṣurrušu ‘to grow shoots’ are clearly related to it. If one surmises that the meaning “protuberance” is original, we would be faced with a shared semantic innovation in PWS, but in view of ṣa-ra-sa-tum = ZÚ.GUL in VE 227 and related forms discussed in Krebernik 1983:10 and Conti 1990:101, the opposite possibility, viz. semantic marginalization of an original anatomical term in Babylonian, may appear more attractive. 

Akkadian
ṣiršu - protuberance (CAD Ṣ 209, AHw. 1093)
On relation with PS *ṣ̂irš- ‘molar’ see SED I No. 275.
Akkadian
ṣurrušu - to grow shoots, branches (CAD Ṣ 260, AHw. 1115)
Ebla
za-la-šum /ṣaršum/ - molar tooth (VE 227, Kogan–Krebernik 2021b: 684)
cf. za-rí-iš-tum /ṣarištum/, za-ra-sa-tum /ṣaraš(a)tum/ (VE 227; Conti 1990:101)
Syriac
ˁaršā - molar tooth (LSyr. 551, SL 1144)
Maalula
ˁerša - (Eck­-)Zahn ((canine) tooth) (GNDM 6)
Mlaḥso
ˁarše (pl.) - Zähne (teeth) (Jastrow 1994: 167)
Turoyo
ˁaršo - Zahn (tooth) (RW 12)
Arabic
ḍirs- - tooth; molar (Lane 1785)
Sabaic
ˀ-ṣ̂rs₁ - molar tooth (SD 42)
Geez
ṣ̂ərs - molar tooth (CDG 153, LLA 1328)
Mehri
məẑrāḥ - tooth (ML 478)
Jibbali
məẓ̂rέš - molar tooth (JD 327)
Harsusi
mǝẑreḥ - molar tooth (HL 152)